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More recently Pfizer has reported development of a humanized GHR monoclonal antagonist antibody (RN172), which blocked GH signaling in vitro and reduced IGF1 production in monkeys following a single-intravenous injection

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doi:10.1016/j.tplants.2012.03.004

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Animal studies confirm its pro-regenerative profile across cutaneous, musculoskeletal, and vascular models

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