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It is presumed that the lipoyl bearing domains LBDs (L1, L2, and L3) and 60 subunits of the transacetylase seem to form a free circulation of lipoyl groups among which the acetyl groups are freely exchanged [18] and shuttle between the active sites of the three catalytic components of the PDC during the oxidative decarboxylation cycle [19]

PMID: 197 NagasawaSKashimaYSuzukiASuzukiY

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Notably, LA, while remaining relatively stable in its solid state, undergoes polymerization when subjected to temperatures exceeding its melting point (47.5 C) or when dissolved in a neutral solution under the presence of light [30]

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Normal muscle maintenance following physical activity*1,3,10