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The development of GLP-1 receptor agonists for type 2 diabetes was contextualised within the broader research landscape, including orally bioavailable agonists, allosteric modulators, and unimolecular multi-agonists all of which use the native GLP-1 receptor as their primary target

2020 May;8(5):377-391

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Known GLP-1 side effects include: nausea, vomiting, diarrhea, dizziness, increased heart rate, infections, headaches, indigestion, pancreatitis, medullary thyroid cancer, sudden kidney injury, worsening diabetic-related retinopathy, shortness of breath, wheezing, hives, difficulty swallowing, rash, abdominal pain and feelings of doom or dread