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But in contradiction to other studies, alogliptin (25 mg/d for 48 weeks) drug did not respond

Free Radic Biol Med 51:11061115 Mailloux RJ, McBride SL, Harper ME (2013) Unearthing the secrets of mitochondrial ROS and glutathione in bioenergetics

This feed-forward mechanism is particularly damaging for dopaminergic neurons as their already high metabolic burden makes them unable to withstand this additional loss of GSH, resulting in apoptosis (Gabby et al., 1996)

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