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Hepatic clearance accounts for roughly 25% of total apixaban elimination, primarily through CYP3A4 with minor contributions from CYP1A2, CYP2C8, CYP2C9, CYP2C19, and CYP2J2 [2]

Aliquots were spotted onto P81 phosphocellulose filters, which were then washed three times for 10 min each in 75 mM phosphoric acid, followed by a 5-min wash in methanol

Jun 30 1993;79(3):202-204

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These compositions may also be referred to using IUPAC nomenclature as S-alkanoyl glutathione compositions