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Steve Small: Yeah, well, thats a good question because looking into this, Don, I did find a recent observational study back in November 2025 that looked at over 400,000 patients taking GLP-1 agonists such as semaglutide to see if they had a higher risk of the side effect

E., & Moutsopoulos, H

Kang S, Voorhees JJ

Twenty participants were randomized to Phase II to account for potential withdrawals

Certainly, there seems to be a mismatch between the influence of high UA and that of gout in risk of PD, as mentioned above

However, because drug levels drop between doses, they have less effect overnight on fasting glucose