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Although we cannot rule out that the increased production of ROS in 3D culture conditions may not be observed under hypoxia, it should be noted that hypoxia itself induces ROS production in numerous cell types, including tumor cells [39]

preclinical safety evaluation found no genotoxicity, mutagenicity, or organ toxicity at tested doses

Post-treatment of Gastrodiae Rhizoma extracts also attenuated the elevated JNK signal pathway activity [28]

Science 114:9495

By reducing oxidative stress and blocking melanin production, many patients notice a clearer, brighter complexion

IGF-1, also called somatomedin C, is a hormone with a similar molecular structure to insulin