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The dashed black curves show the responses of GSH and fractional hepatocytes to rescue by the standard dose of NAC (36 mM) given over a 1 hour time period starting at two hours after the APAP dose
Note that due to the relative small size of the rats, rat fistulas regularly appeared as large and complex, and thereby, in this respect, corresponded to the worst presentation in the patients (Klicek et al., 2008
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Monoclonal antibody therapeutics with up to five specificities: functional enhancement through fusion of target-specific peptides
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