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It belongs to a class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists , which work by mimicking the action of a naturally occurring hormone that regulates blood sugar levels and appetite

Pathophysiology of oxidative stress According to the oxidative stress hypothesis, oxidative damage can be induced by unrestricted production of ROS as well as other oxidants, for instance, reactive lipid species and reactive nitrogen species (RNS) [16]

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Seek urgent medical advice (contact 999 or attend A&E) if you experience: Severe chest pain or pressure, particularly if radiating to the arm, jaw, or back Sudden severe headache with visual disturbances, confusion, or difficulty speaking Symptoms of stroke , including facial drooping, arm weakness, or speech difficulties Severe shortness of breath or difficulty breathing at rest Loss of consciousness or severe dizziness with falls Seek same-day medical assessment if: Your blood pressure reading is 180/120 mmHg or higher You have signs of possible target organ damage (new confusion, chest pain, significant shortness of breath) Contact your GP or diabetes specialist nurse within 24-48 hours if you notice: Persistent elevated home blood pressure readings (consistently above 135/85 mmHg) New or worsening symptoms such as regular headaches or visual changes Palpitations or irregular heartbeat that is frequent or concerning Unexplained swelling of the ankles, legs, or abdomen Unusual fatigue or weakness that interferes with daily activities Routine review is appropriate for: Gradual changes in blood pressure that remain within acceptable ranges Questions about medication interactions or side effects Planned adjustments to diabetes or blood pressure medications General concerns about cardiovascular health Patients should maintain a symptom diary if they experience any unusual symptoms after starting Rybelsus, noting the timing, severity, and any associated factors