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3) is the maintenance of tissue homoeostasis at all the levels of CNS organisation, from molecular (ions, metabolites, and neurotransmitters, etc.), to network (regulation of synaptic connectivity), to organ (formation and maintenance of bloodbrain barrier and glymphatic clearance system) and systemic (chemosensing blood oxygen, Na + , CO 2 or glucose)

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Many of this studys subjects also had ligament sprains and tendon issues, which often heal on their own over time, so its unclear if these improvements were due to the peptide or just the passage of time (the study had no control group)

[59] Compounded drug versions of semaglutide have been created and made widely available, albeit without approval

Diabetologia 1995