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First, it is an endogenous molecule: it circulates in human plasma at a concentration of roughly 200 ng/mL around age 20, declining to about 80 ng/mL by age 60, a fall that has been linked, at least associatively, to the general decline in tissue regenerative capacity with age

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The sample was prepared in D 2 O for 1 H NMR

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The use of recombinant human growth hormone to protect against muscle weakness in patients undergoing anterior cruciate ligament reconstruction: A pilot, randomized placebo-controlled trial