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Comparison of glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter protein-2 inhibitors on treating metabolic dysfunction-associated steatotic liver disease or metabolic dysfunction-associated steatohepatitis: systematic review and network meta-analysis of randomised controlled trials

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Tirzepatide , a dual GIP/GLP-1 receptor agonist, demonstrated superior efficacy to semaglutide in a landmark head-to-head trial, with patients receiving ZEPBOUND losing an average of 50 pounds over 72 weeks compared with 33 pounds among WEGOVY-treated patients

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i.e., quick progressive (spermatozoa moved quickly in a linear way), slow progressive (spermatozoa moved slowly in a linear way), non-progressive (spermatozoa showed circular movements), and immotile (spermatozoa had no circular and linear movements)

Reciprocal metabolic reprogramming through lactate shuttle coordinately influences tumor-stroma interplay