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Initial weight reductions often include water loss and decreased bloating from reduced food intake, followed by gradual fat loss

The 2024 EMA review of GLP-1 receptor agonists found no causal link to suicidality, and ongoing FDA analyses have not confirmed one either

d Absolute effect size (95% CI) based on the mentioned ANCOVA models

This raises the possibility that GLP-1s could influence the gut-immune axis, which is often disrupted in autoimmune diseases

Building on prior discussions of systemic disease interactions with retinal health, the study finds no clear increase in neovascular AMD risk