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doi: 10.1016/j.ccr.2013.08.020 56 BadgleyMAKremerDMMaurerHCDelGiornoKELeeHJPurohitVet al
In laboratory and pre-clinical research settings, FOXO4-DRI is used as the primary peptide tool for selective senescent cell elimination a strategy known as senolysis
DSIP therapy is not intended to diagnose, treat, cure, or prevent any disease
albicans ) can be commensal when the host is healthy, but they can invade and cause infection when the intestinal barrier function is impaired and/or the hosts immune function is weakened 109
The oxidative stress caused by a decrease in GSH levels can then impact microglia function and potentially lead to a more pro-inflammatory M1 phenotype that has reduced -amyloid clearance capabilities (Vilhardt et al., 2017)
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