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doi: 10.1016/j.ejphar.2020.173581 82 TeramotoSMiyamotoNYatomiKTanakaYOishiHAraiHet al

FDA approval was based on the SOUL cardiovascular outcomes trial (CVOT) that demonstrated a 14% relative reduction in risk of MACE in patients treated with Rybelsus 14 mg orally once daily for approximately 5 years compared to those who received placebo

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Generic versions appeared relatively quickly on the diabetes side because Novo Nordisk partnered with Teva Pharmaceutical Industries to help manufacture and distribute an authorized generic

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This allows for greater spontaneity compared to some oral sexual health medications