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The $149 introductory rate applies to 1.5mg and 4mg doses for the first four months, with prices increasing as patients move to higher, longterm doses

SCLA2a was able to pull down GPX4, and GPX4 pulldown was prevented by preincubation with RSL3 or SCLA2 (Extended Data Fig

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GLP-1 medications can modestly improve lipid profiles, particularly by reducing triglycerides and, in some cases, LDL cholesterol

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