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"But microdosing has not been well studied in clinical trials, and most of the data is anecdotal." She said that when someone asks her about microdosing a GLP-1, she advises that, since it's off-label (meaning not approved by the FDA), carefully monitoring their blood sugar, weight, and symptoms is essential
However, this drug can cause side effects such as nausea and vomiting, which can affect patient adherence to the treatment
Most people underestimate how much technique matters until they experience severe nausea from injecting too quickly or bruising from incorrect needle angles
Hartz AM, Zhong Y, Wolf A, LeVine H 3rd, Miller DS, Bauer B
In the SURMOUNT-5 trial, it resulted in a 13.7% weight reduction at 72 weeks, with 60.5% of participants losing at least 10% and 27.3% losing 20% or more
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