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MARKET TRENDS IN GLP-1 USAGE Recent market data suggest that around 5% of US adults (approximately 12.5 million people) have used or are currently using GLP-1s for weight loss alone.3 This is higher than the 7.4 million4 people (both adults and children) using insulin and equal to the 5% who have used or are currently using GLP-1s solely to treat a chronic condition such as diabetes or heart disease approximately 3% are using GLP-1s to both treat a chronic condition and to lose weight

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Because HepG2 cells possess higher CYPOR activity than primary hepatocytes (Schulz et al