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Microdosing GLP-1 Receptor Agonists During Perimenopause: A Clinical Approach to Hormonal Weight Gain Written and edited by Sarah Bonza MD, MPH, FAAFP, MSCP, DipABLM, NBC-HWC Perimenopause represents a challenging time for women, with up to 70% experiencing weight gain due to declining estrogen levels, decreased energy expenditure, and metabolic changes
Most people notice subtle changes within 4-6 weeks of consistent use
Delayed gastric emptying is the biological process where GLP-1 receptor agonists slow the rate at which food and medication leave the stomach to promote prolonged satiety
Concentration used: Higher concentration products may produce faster visible results, though the ceiling effect means 3% does not work three times faster than 1%
There is reasonable scientific basis to expect that the GLP-1 component will confer similar cardiovascular protection
Type of study: non-rct experimental Number of citations: 0 Year: 2024 Authors: Weiyi He, Chi Zhang, Huijung Lai, Guopeng Wu, Ming Xiong, Hui Peng, Ming Chen, Ke Wang Journal: Drug delivery and translational research Journal ranking: Q1 Key takeaways: Sph_12-38 combined with sponge spicules effectively treats acne, with a cure rate of 100% in vivo for rabbit ear acne after two weeks
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