There is not enough research to confirm safety, so it is generally not recommended
Furthermore, as for cardiac fibroblasts, GLP-1RAs inhibit Ang II and glucose-induced collagen formation via decreasing phospho-NF-B-p65 and phospho-ERK1/2 expression [169] (Figure 2)
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Ultimately, this could reduce development costs and timelines, enable investment in additional biosimilar programs, accelerate innovation, and most importantly, improve patient access to affordable biologic therapies