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Preclinical studies in rodents have shown an association between GLP-1 receptor activation and thyroid C-cell changes, although a direct causal link in humans has not been established, and UK/EU SmPCs for authorised GLP-1 RAs do not list MTC or MEN2 as a formal contraindication
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(2024) 11:e2305563
The integration step used in this run was 1 fs
GLP-1 receptor activation in the spinal cord and brainstem may be anti-inflammatory and pain-relieving, while effects on peripheral sensory neurons may, under certain conditions, produce sensitization
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