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Rare loss of function variants in the hepatokine gene INHBE protect from abdominal obesity

The role of oxidative stress in the pathogenesis of COPD: implications for therapy

Published Research Lipolytic Activity Heffernan et al

UCP1 transcript abundance does not necessarily predict protein abundance, and protein abundance alone does not prove increased thermogenic flux

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Its proposed mechanisms are complex and multifaceted, involving interactions with the nitric oxide (NO) system, influence on growth factor expression (like Vascular Endothelial Growth Factor or VEGF), and modulation of cellular pathways related to tissue repair