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Available as both an injection and an oral pill, semaglutide mimics the natural hormone GLP-1, effectively curbing your appetite and promoting sustained weight loss

This evolution will be driven by expanded clinical evidence, development of cardiovascular-specific treatment protocols, and modification of reimbursement criteria to include primary prevention of cardiovascular events in high-risk populations regardless of weight loss magnitude

However, she challenges the idea that GLP-1s alone cause this: It does not cause muscle wastingThat is the low-calorie diet that folks end up on when their appetites are crushed out by too high a dose. If you keep a lower dose and ensure people maintain a regular appetite so they can get enough calories and enough protein on board, you could potentially mitigate this side effect, she says

This paper gives it a quantitative grounding

Watch for blood sugar changes

Hvistendahl M, Brandt CF, Tribler S, et al