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One potential silver lining for industry: While the proposed consent order requires the company to have competent and reliable evidence to substantiate weight loss claims, the order returns to a more flexible definition of competent and reliable evidence that does not prescribe any particular type of test and instead requires tests, analyses, research, studies, or other evidence based on the expertise of professionals in the relevant area, that (1) have been conducted and evaluated in an objective manner by qualified persons and (2) are generally accepted in the profession to yield accurate and reliable results. Followers of this blog will recall that the previous administration announced a sweeping overhaul of longstanding FTC guidance on health claims that attempted to ossify the formerly flexible substantiation standard.

The most common denial reasons in 2026 are insufficient BMI documentation, missing comorbidity ICD-10 codes, lack of lifestyle intervention notes, and step therapy not completed

Chemello, F., Bassel-Duby, R

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GIP and GLP-1 receptors are also abundantly expressed on beta-cells in the islets of Langerhans

In studies with rodents, GLP-1 medicines caused thyroid tumors, including thyroid cancer