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A fatty acid chain is attached to the peptide, which allows it to bind to albumin in the blood

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"De-registration of pharmaceutical products containing sibutramine" (Press release)

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Emphasis on mechanistic endpoints and histological markersnot medical use claims

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Patients should seek urgent medical attention for severe or persistent abdominal pain, repeated vomiting, or signs of dehydration, as these may indicate pancreatitis or gallbladder disease

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