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However, ongoing debate centers on whether the benefits of uric acid-lowering therapy stem from decreased uric acid levels or the inhibition of XO activity

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It remains the largest source of nitrogen in the body for NO production

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Then slides were rinsed three times with Tris buffer, covered with Fluorescence Mounting Medium (Dako, Hamburg, Germany) and examined under an Axio Imager Microscope (Carl Zeiss, Jena, Germany)