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Overall, these findings collectively demonstrate that the molecular ruthenium catalyst Ru(II)-OH and the nanoparticle formulation NP2 are therapeutically active in a 21% O 2 atmosphere, but these lose their therapeutic efficiency in a 1% O 2 atmosphere
Maturation skews macrophage polarization from M1 to M2 (interleukin-4 [IL-4], interleukin-10 [IL-10], IL-12, Arginase 1 [Arg-1]
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