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During the early phase (weeks 1-4), most people lose 2-5 pounds as hunger decreases and calorie intake drops naturally

Vitamins or mineral infusions might take longer (around 45-60 minutes) since they sometimes involve larger volumes or thicker solutions

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The depressive brain has been shown to exhibit a decrease in hippocampal neurogenesis, and this reduction is recovered by antidepressant drug treatment (Tanti and Belzung, 2013)