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Tirzepatide is a synthetic 39-amino acid peptide that acts as a dual agonist at both the GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 receptors
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Since May 2025, it has discontinued compounded semaglutide to align with the FDAs rules and regulations
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Retatrutide is an investigational triple receptor agonist developed by Eli Lilly that targets GLP-1, GIP, and glucagon receptors, giving it a broader metabolic mechanism than single- or dual-pathway therapies
The skin must be clean, completely dry, and free of any oils, lotions, or creams
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