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Enhances immune system, metabolizes toxins, and helps support liver detoxification

Lilly noted, however, that dropouts were highly correlated with baseline BMI and included discontinuations for perceived excessive weight loss. The company also pointed out that participants with a higher BMI were less likely to drop out

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They can protect lean body mass and micronutrient status during weight loss (which is often rapid with GLP-1s)

Overall, the weight of evidence to date does not support a role for FGF21 in mediating bone remodeling in adult humans