RK00029), IL-6 (Biosourse, cat no
The primary outcome was percentage change in body weight from drug initiation to 1 year
We evaluated six distinct gastrointestinal and systemic adverse events, which were designated as primary outcomes in our review
Alex Spencer (Metabolic Psychiatrist) Should Psychiatrists Prescribe GLP-1s? (drlewis.com), January 4, 2026
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However, despite the rather modest weight loss with the drug in this trial, these patients with preserved ejection fraction heart failure demonstrated clinically significant improvements in quality of life, measures of functional capacity, reductions in important biomarkers including NT proBNP and CRP, and numerically less likelihood of heart failure decompensation. In the published paper, the researchers hypothesize that the weight-loss-independent benefits of semaglutide in HFpEF may include direct effects on decongestion