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Someone with the MTHFR gene variation will have lower levels of methionine, and homocysteine can build up to toxic levels, which have been associated with inflammation and heart disease
H.XiaoJ.et al (2023)
Data were analyzed using Prism version 6.05 software (Graph Pad, San Diego, California)
Limitations include limited large-scale human clinical evidence, challenges in extrapolating in-vitro concentrations to in-vivo contexts, stability sensitivities (light, heat, alkaline pH), and variability in supplier purity
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