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De gunstige effecten van zowel acute als chronische L-Carnitine tekorten in verschillende pathologische aandoeningen zijn goed gedocumenteerd, zoals infectieziekten, hemodialyse, kanker en dystonie

Other than patients who have had their stomachs bypassed, there is also an autoimmune condition known as pernicious anemia that leads to a deficiency of intrinsic factor, lack of ability to absorb vitamin B12 and therefore poor availability of cobalamin (vitamin B12)

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This study demonstrated that cultured hepatocytes treated either with a precursor of GSH, such as L-cysteine or N-acetylcysteine, or with its soluble ethyl ester form, boosts the levels of cellular GSH, which upregulates CYP27A1, CYP27B1, and VDR but downregulates CYP24A1

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J., 113, 123-130, (1969)