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Support of Cellular Longevity and Mitochondrial Function In animal studies, prolonged administration of Epithalon was associated with increased lifespan and improved markers of physiological function in aging rodents

The GLP-1 receptor activation slows gastric emptying, reduces appetite, and improves insulin sensitivity

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Deficiency of L-Arginine leads to L-arginine is an essential amino acid that plays several vital roles in the body, including protein synthesis, wound healing, and immune system function

For those with hypermobility and EDS specifically, Id flag the following as the minimum due diligence before starting these medications: A thorough GI history and ideally gastric emptying assessment if theres any existing dysmotility Baseline muscle mass measurement (DEXA or similar) given the sarcopenia risk A clear plan for high-protein diet and resistance-based exercise to mitigate muscle loss Baseline bone density if theres any existing concern Consideration of the nutritional picture specific to hypermobility, since these drugs can affect appetite and nutrient absorption A conversation specifically about MCAS if thats a feature of your presentation The medication options for hypermobility and EDS are limited and often unsatisfying, and its entirely understandable why people are looking at something new with genuine curiosity

Keep a bottle within reach on the nausea-prone days right after each dose increase