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However, due to its moderate cholesterol-lowering effect, QT interval prolongation, and insufficient clinical evidence for cardioprotective effects, probucol has not achieved widespread clinical adoption

Osna NA, Donohue TM Jr, Kharbanda KK

But the medication alone is not a magic pill

The process of transamination by GOT1 results in the generation of -KG and aspartic acid (Asp), thereby contributing to the maintenance of the TCA cycle

Also, transition to maintenance protocol

Typical Timeline for Nausea After the First Dose Every individual responds differently to medication, but clinical data and patient reports provide a general timeline for what to expect