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In contrast, when utilising 30% U- 13 CR 6 -labelled arginine as the sole carbon source, there were only a few differences between the metabolic labelling in gdh3 / gdh3 and wild-type cells that included two TCA cycle intermediates (fumarate and cis -aconitate) and all three aromatic amino acids (phenylalanine, tryptophan, and tyrosine)

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The amino acid glycine has also been shown to delay the progression of cataracts in a rat model of diabetes (63)

Standard treatmentsrest, ice, anti-inflammatories, and physical therapyprovide symptom relief but do little to address the underlying hypovascularity