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Theoretical concerns: angiogenic activity warrants caution in patients with active malignancy (no tumour-promoting effects observed in any preclinical study, but oncology populations have not been formally studied)
showed that early metastatic breast cancer cells had unique stem-like gene expression characteristics and prefer to proliferate and differentiate to produce advanced metastatic disease at the single-cell level (124)
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neoformans heat shock response appears to generally resemble those of other organisms, consistent with the highly conserved nature of the heat shock response and the need to induce conserved protein chaperones
[DOI] [PubMed] [Google Scholar] Monks TJ, Ghersi-Egea JF, Philbert M, Cooper AJ, Lock EA
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