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Pinto-Junior DC, Silva KS, Michalani ML, Yonamine CY, Esteves JV, Fabre NT, et al

To optimize effective absorption, patients are required to adhere to complicated dosing conditions of taking the drug in a fasting state (at least 30 minutes before any food intake) with no more than 4 ounces (approximately 120 mL) of plain water

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the name suggests California-specific handling, though this wasn't independently confirmed

This targeted approach makes it a more refined and potentially safer option for weight loss

METHYLSULPHONYLMETHANE (MSM), PIPER NIGRUM EXTRACT (BIOPERINE)