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[PMID: 8611505] PubMed record related to this compound for laboratory literature review

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Figure 13 illustrates the effects of prenatal exposure to VPA, showing that HDAC inhibition may exacerbate oxidative stress by dysregulating the expression of genes involved in the antioxidant response, thereby promoting redox imbalance through increased ROS production and impaired antioxidant defenses (Gottlicher 2001

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The inflammatory mechanisms that damage cells, tissues, and organs in these chronic conditions are perpetuated in part by increased oxidative stress and lowered intracellular GSH pools

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