Trial protocols specify gentle swirling rather than shaking
Croatian researcher Predrag Sikiric and colleagues at the University of Zagreb have published the bulk of the animal research over roughly three decades, with studies covering tendon healing, gastric ulceration, colitis, brain injury, and systemic organ protection in rodent models
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You don't know the purity, you don't know if there are contaminants, and you can't trust your data
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So, there is no risk of overdose