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Hydration and Fiber: Your First-Line Defense Increasing water intake to 8-10 glasses daily is the single most effective non-medication strategy for semaglutide-related constipation

26 MarsoSPDanielsGHBrown-FrandsenKKristensenPMannJFNauckMAet al

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Semaglutide can also delay the absorption of some oral medications due to its effect on gastric emptying, which may require monitoring for drugs with a narrow therapeutic index

Abdominal Pain Abdominal pain or discomfort (20% with Wygovy) is another potential side effect that may arise from the use of semaglutide

Its definitely different because theres no sense of restriction