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Age-related anabolic resistance and reduced baseline muscle reserve may increase susceptibility to lean mass loss during medically induced weight reduction [40]

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They are usually mild and temporary

The slight cytotoxic effect of sulindac concerning C32 cells is a consequence of the production of a large amount of Bcl-2 protein in response to the action of the drug, inhibiting the initiation of the apoptosis process, and lack of influence on the level of the pro-apoptotic protein Bax

Light walking after meals promotes digestion and may reduce queasiness

The trial was conducted in accordance with the Declaration of Helsinki and Good Clinical Practice guidelines