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Correspondingly, novel evidence shows that another androgen, dihydrotestosterone, can increase migration and invasion via ZIP9-mediated intracellular Gi/MAPK/MMP9 signaling in bladder cancer
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caution advised
Melanotan II is a non-selective pan-melanocortin agonist (MC1R+MC3R+MC4R+MC5R), whereas PT-141 (Bremelanotide) is more selective for MC3R/MC4R with minimal MC1R activity
Practical result: Better visceral fat targeting during GLP-1 protocols, particularly in the later phases when the easy fat has already come off
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