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In the SURPASS-2 diabetes trial, an open-label 40-week study randomised 1,879 patients with type 2 diabetes to tirzepatide 5, 10, or 15 mg or to semaglutide 1 mg
Semaglutide comparison including 30,074 and 29,071 individuals, respectively, before matching (Supplementary Data 4)
Figure 2
This principle applies to all peptides, not just tirzepatide
PEP, prolyl endopeptidase
And if your health history puts you at high risk (thyroid cancer, pancreatitis, pregnancy), GLP-1s are not for you
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