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When taken as a weekly injection, it helps regulate blood sugar levels, slow down the rate at which food is digested, and increase fullness after you eat

It prompts the pancreas to secrete insulin, suppresses glucagon, slows gastric emptying so food stays in the stomach longer, and acts on receptors in the hypothalamus and brainstem to reduce appetite

It can be very difficult to lose and maintain a healthy weight

Neither compound has published the kind of long-term hard-outcome data (cardiovascular events, mortality) that ultimately defines a metabolic drugs value, because both are too early in development for that

& Burne, T