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Li ZY, Zhang N, Wen S, Zhang J, Sun XL, Fan XM, Sun YH (2017) Decreased glucagon-like peptide-1 correlates with abdominal pain in patients with constipation-predominant irritable bowel syndrome
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Reducing from 50 units to 40 units (4.0 mg at 10 mg/mL) or even 35 units (3.5 mg) can dramatically improve tolerability while maintaining meaningful therapeutic effect
International Consensus Development International guidelines have shown similar evolution toward continuation with risk mitigation (Table 2)
Horowitz M, Rayner CK, Marathe CS, Wu T, Jones KL (2020) Glucagon-like peptide-1 receptor agonists and the appropriate measurement of gastric emptying
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