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Healthcare professionals should counsel patients that whilst these cosmetic concerns are valid, they represent a common consequence of therapeutic weight reduction rather than a direct drug effect on skin structure

Twenty-two percent of large firms say that new prescription drugs contributed a great deal to higher premiums, 36% say that they contributed somewhat to higher premiums, 17% say that they contributed very little to higher premiums, and 9% say that contributed not at all [Figure 13.1]

If nausea becomes severe or persistent, it is important to consult your GP, as dose adjustment or additional supportive measures may be required

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5.6% reported using them for 12 months