10.1002/jbt.22942 45 LuB.LiJ.GuiM.YaoL.FanM.ZhouX.et al (2022)
After treatment with CPP-CAND, a significant reduction of approximately 7.1-fold in the number of FOXO4 foci was observed in the nuclei of the senescent cells
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It also has significant antioxidant effects and has been shown to inhibit carcinogenic receptor expression, which has led to research into its potential anti-tumor effects in breast and colorectal cancer [5, 6]
Q-PCR reaction mixtures contained 1 l cDNA, 1x SYBR Green Supermix (BioRad, Hercules, CA), and 0.15 M gene-specific primer sets in a total volume of 25 l
Likewise, decreased gene expression of Egr was evident at 24 h in the inferior caval vein, Vegfr expression was decreased at 1 h and 24 h in all vessels, and Plc gene expression was decreased at 24 h in the inferior caval vein