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In vitro stimulation of human and murine macrophages and monocytes have demonstrated a proinflammatory effect of G6PD overexpression and a corresponding dampened response with G6PD-d 110

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10.12659/MSM.882125 84 KongQ.WangB.TianP.LiX.ZhaoJ.ZhangH.et al (2021)

[1] Published evidence for 5-Amino-1MQ comes mainly from enzyme tests, cultured cells, and mouse studies

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Research needs to investigate dosage, timing, reproductive outcomes, and safety, such as impacts on pregnancy and offspring development