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Native -MSH is a 13-residue linear tridecapeptide rapidly degraded by serum proteases

As noted by Manasyan et al., while these agents reduce insulin requirements and maintain adequate glucose control with fewer hypoglycemic events, they may simultaneously impede adequate nutrition as a result of delayed gastric emptying and present a risk of aspiration

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Kshattry, S., Saha, A., Gries, P., Tiziani, S., Stone, E., Georgiou, G